
Article by Dr Suman Gupta
Dr Suman Gupta, a Functional Medicine Doctor, explains natural ways to boost melatonin levels to achieve better sleep.
Hormones work in symphony with each other to create balance and harmony within the human body. Sleep stems from this perfectly aligned hormonal balance, led by melatonin, our sleep hormone; enabling the mind to switch off and the body to rest. Miraculous processes occur during these seven to nine hours, shaping our mood and energy as we awake.
Staying awake throughout the day is hard work. The body is running a constant marathon on the inside; each cell processing complex biochemical reactions essential for everyday living. The human body certainly couldn’t sustain this for 24 hours on end. Sleep allows for the cells to repair, toxins to be removed, the brain to reorganise and hormones to regenerate. Thus, enhancing our mood and re-energising us, ready for the new day.
Our body has an inner 24-hour clock, known as the circadian rhythm. The primary hormone in regulating the circadian sleep-cycle is Melatonin. Darkness stimulates melatonin production, which in turn sends a message to the brain signalling us to fall asleep. Melatonin production, within the pineal gland, continues throughout the night, tailing off during the early hours of dawn as light creeps in. The synergistic dance between cortisol (alert hormone) and serotonin (happiness hormone), then takes control to awaken us filled with energy and joy, welcoming us into the new day. As the evening light falls, serotonin conversion into melatonin begins, and the hormonal sleep dance begins again. It is this interplay of hormones that enhances our mood and impacts our overall health and well-being.
The link between inadequate sleep and mood has been well researched and documented. Sleep deprivation results in the inability for the human mind and body to fully reset. The brain processes emotions while we sleep. Thus, a lack of sleep can result in heightened emotions, irritability, mood-swings and low resilience. Most of us have experienced those distressing mornings of being woken by the blaring alarm clock, desperate just to creep back under the warm duvet for a few more minutes. This depleted morning energy accompanies the abrupt mood; and overdosing on flat whites seems the only feasible option to momentarily mask the deeper blues in a bid to survive the day.
Studies show that chronic insomnia is associated with mental health issues including depression and anxiety. The exact mechanism is poorly understood, but it is likely that inadequate sleep disrupts melatonin and serotonin production. Low levels of these happiness and calming hormones can cause interference in human behaviour and psychology resulting in mental health issues. Depleted melatonin levels also have a knock-on effect on our sexual hormones which can contribute to menstrual dysregulation and premenstrual syndrome in women, further dampening mood.
Chronic stress is the number one cause of sleep deprivation and is regarded a twenty-first century health epidemic. The high cortisol levels released during a prolonged stress state, exert negative effects on the circadian rhythm. Other melatonin blockers include blue light emitted from our mobile devices, environmental toxins and poor nutrition. All these modern-life melatonin disruptors work together to take us onto a new negative sleep-cycle journey.
Hormones are deeply interconnected with sleep, mood, and overall well-being and we can all strive to achieve optimal health and happiness.
Functional medicine understands that melatonin production also occurs within the gut cells. Gut absorption is crucial for providing the body with the essential vitamins and minerals involved in the complex reactions of melatonin synthesis. Stress pathways compete for and exhaust these essential nutrients. Therefore, optimising gut health and reducing stress is central to obtaining a good night’s sleep. Understanding this human pattern empowers us to make better lifestyle and nutritional choices to improve our mood and overall health and wellbeing.
Melatonin is in fact a super-hormone with multiple benefits outside of the sleep-cycle. There are numerous studies showing the importance of melatonin in anti-ageing, brain cell regeneration, boosting immunity, hormonal balance, optimising gut health, and improving resilience; all of which also affect our mood balance.
Tryptophan is an amino acid that helps produce melatonin.
B-vitamins facilitate the conversion of melatonin from serotonin.
Melatonin is also produced within the gut.
Blue light blocks melatonin production.
Warm baths and magnesium help relax the body and muscles.
Meditation reduces stress hormones, which can block the production of melatonin.
Acupressure stimulates the parasympathetic system triggering deep relaxation.
Melatonin synthesis peaks in the early hours and then begins to slowly decline.
Sunlight is required to produce serotonin which converts into melatonin.
More tips can be found on Instagram @functionaldoctoruk.
Dr Suman Gupta is a leading expert in the field of Functional Medicine with over 18 years’ experience as an NHS GP. She has helped thousands of people reverse chronic disease and reach their optimal health by getting to the root cause through ground-breaking comprehensive testing and formulating individualised treatment options.
She is the founder of the London Functional Doctor clinic www.functionaldoctor.co.uk; which provides lifestyle and nutritional treatment packages to optimise health and well-being. Regulated by the Care Quality Commission (CQC) for its management and governance, Functional Doctor is also in the process of launching nationwide online well-being packages as an introduction to Functional Medicine.
November
06nov10:0015:00CPD Accredited Menopause Champion Course
06/11/2025 10:00 - 15:00(GMT+00:00)
Join us on our CPD Accredited Menopause Champion Course Our course includes practical tools, DEI considerations and step-by-step guidance to help Champions feel confident and equipped to offer real support — not just awareness. Here’s what’s included: Understanding Menopause
Our course includes practical tools, DEI considerations and step-by-step guidance to help Champions feel confident and equipped to offer real support — not just awareness.
Here’s what’s included:
Understanding Menopause
– Key stages and common symptoms
– How menopause impacts work and wellbeing
Diversity in Menopause
– Different experiences across cultures, health, age, and gender identity
Managing Menopause
– Overview of HRT, natural options, and practical strategies
Navigating GP Appointments
– How to self-advocate, track symptoms, and prepare for appointments
Supporting Colleagues
– Fostering openness, having sensitive conversations, and making adjustments
Creating Menopause Action Plans
– Step-by-step template to ensure support and inclusion
Championing Inclusion
– Guidance for supporting neurodivergent, disabled, diverse, LGBTQ+, and frontline staff
Your Role as a Champion
– Responsibilities, boundaries, signposting, and building trust
The course also includes:
✅ A Menopause Action Plan template
✅ Navigating GP Appointments document
Plus loads more free resources!
DATE: Thursday 6th November
DATE: Wednesday 17th December
Place: Zoom
Time: 10.0am – 3.00pm
Cost: £395 (including certificate)
19nov10:0013:00MenoMinds – Free Training for Women in Business | Menospace & Minds That Work
19/11/2025 10:00 - 13:00(GMT+00:00)
Introducing MenoMinds – Free Training for Women in Business We’re excited to share MenoMinds, a fully funded programme created by Menospace and
We’re excited to share MenoMinds, a fully funded programme created by Menospace and Minds That Work, supporting women in business, freelancing, or entrepreneurship through the emotional and mental challenges of menopause.
Wednesday 19th November | 10:00am – 1:00pm (UK)
Live on Zoom | 💷 Free (funded by NEBOSH’s Social Purpose Programme)
Menopause can affect confidence, focus and wellbeing — MenoMinds helps you take back control with practical tools and a supportive community.
You’ll explore the CARE Framework:
Includes a digital workbook and invitation to monthly community groups on sleep, nutrition and stress management.
Freelancers, entrepreneurs, and women in small or micro-businesses (under 50 employees).
Facilitators: Haley White (Menospace) and Victoria Brookbank (Minds That Work)
19nov12:3018:00Masculinity in the Workplace - 2025 (In-person)
19/11/2025 12:30 - 18:00(GMT+00:00)
Conway Hall
25 Red Lion Square, London, WC1R 4RL
Brought to you by Token Man and The Hobbs Consultancy. Welcome to Masculinity in the Workplace, designed specifically to

Welcome to Masculinity in the Workplace, designed specifically to engage men with creating inclusive cultures. Marking International Men’s Day, the objective of our event is to give men both the reason and the skills to lean into the conversation, while also providing women and non-binary people with the confidence to engage more men in culture change. Because ultimately we can only make real change by working together.
Date: Weds Nov 19 2025
Time: 12.30pm to 6pm
Location: Conway Hall, 25 Red Lion Square, London, WC1R 4RL
Our speakers will share their insights and experiences, shedding light on the evolving dynamics of masculinity, leadership and culturein diverse work environments. You’ll have the chance to ask questions, participate in interactive sessions, and network with like-minded professionals.
The theme for this year is ‘Supporting Boys to Men to Role Models’. This year’s event will seek to understand the concerns and barriers that are in the way for boys and men, particularly looking at key inflection points in their lives. It will equip parents, leaders, friends and persons of significance in the lives of young men with the tools for self-reflection, effective role modelling and courageous conversations..
It will suggest that status-seeking and risk-taking behaviours are innate as boys become men, look at how this shows up for boys in 2025 and question what support could help these boys have a more positive initiation in to adulthood so that they are ready for the workplace. We know that there is a reverse gender pay gap and that schools aren’t preparing students in the same way to enter the professional workplace – what needs to be done?
We will look at the behaviours that are role modelled by men once they are in the workplace. Is it healthy for us to look for male role models, or is a search for positive behaviours more effective? What can we learn from how men are represented on screen and in the media? And what can we do to support our men once they are in the workplace?
This site is for the in-person experience. Otherwise you can register for the online version here.
FYI – lunch will not be provided

This event is for anyone passionate about creating more inclusive, equitable, diverse and human workplaces, and we welcome attendees of all identities and expressions.
Historically, our audience has included around 60% men and 40% women or non-binary people, with a wide range of roles and lived experiences.
This year, we’re especially keen to welcome CEOs, HRDs, CMOs, Inclusion & Diversity leaders, People & Culture teams, and anyone working to engage men more effectively in their organisations. Whether you’re a parent, people manager, or someone invested in systemic culture change, this event is for you.
By attending, you’ll be joining a growing community of people committed to reshaping masculinity, unlocking allyship, and building workplace cultures where everyone can thrive – from boys and young men to senior leaders and everyone in between.
20novAll DayDigital Transformation Conference
20/11/2025 All Day(GMT+00:00)
Mercure London Earls Court
London
Ready to transform your business in the digital age? The upcoming Digital Transformation Conference UK promises an exceptional opportunity for leaders who want to accelerate change, embrace innovation and shape
Explore how industry leaders are redefining digital and business transformation. Learn proven strategies, gain fresh perspectives, and connect with peers shaping the future of technology and enterprise. Tactical & practical content to drive your transformation efforts.
Throughout the day, delegates can look forward to a diverse programme of content exploring every aspect of digital transformation, business change, and innovation. Hear best practices, lessons learned, and insights into real-world challenges from leaders driving progress across digital, technology and IT.
If you’re a C-suite leader, head of innovation, transformation or IT, this is the place to be. Whether you’re just starting your journey or looking to scale up, you’ll leave with fresh ideas, new contacts and a renewed sense of direction.
