Article by Dr Suman Gupta
Dr Suman Gupta, a Functional Medicine Doctor, explains natural ways to boost melatonin levels to achieve better sleep.
Hormones work in symphony with each other to create balance and harmony within the human body. Sleep stems from this perfectly aligned hormonal balance, led by melatonin, our sleep hormone; enabling the mind to switch off and the body to rest. Miraculous processes occur during these seven to nine hours, shaping our mood and energy as we awake.
Staying awake throughout the day is hard work. The body is running a constant marathon on the inside; each cell processing complex biochemical reactions essential for everyday living. The human body certainly couldn’t sustain this for 24 hours on end. Sleep allows for the cells to repair, toxins to be removed, the brain to reorganise and hormones to regenerate. Thus, enhancing our mood and re-energising us, ready for the new day.
Our body has an inner 24-hour clock, known as the circadian rhythm. The primary hormone in regulating the circadian sleep-cycle is Melatonin. Darkness stimulates melatonin production, which in turn sends a message to the brain signalling us to fall asleep. Melatonin production, within the pineal gland, continues throughout the night, tailing off during the early hours of dawn as light creeps in. The synergistic dance between cortisol (alert hormone) and serotonin (happiness hormone), then takes control to awaken us filled with energy and joy, welcoming us into the new day. As the evening light falls, serotonin conversion into melatonin begins, and the hormonal sleep dance begins again. It is this interplay of hormones that enhances our mood and impacts our overall health and well-being.
The link between inadequate sleep and mood has been well researched and documented. Sleep deprivation results in the inability for the human mind and body to fully reset. The brain processes emotions while we sleep. Thus, a lack of sleep can result in heightened emotions, irritability, mood-swings and low resilience. Most of us have experienced those distressing mornings of being woken by the blaring alarm clock, desperate just to creep back under the warm duvet for a few more minutes. This depleted morning energy accompanies the abrupt mood; and overdosing on flat whites seems the only feasible option to momentarily mask the deeper blues in a bid to survive the day.
Studies show that chronic insomnia is associated with mental health issues including depression and anxiety. The exact mechanism is poorly understood, but it is likely that inadequate sleep disrupts melatonin and serotonin production. Low levels of these happiness and calming hormones can cause interference in human behaviour and psychology resulting in mental health issues. Depleted melatonin levels also have a knock-on effect on our sexual hormones which can contribute to menstrual dysregulation and premenstrual syndrome in women, further dampening mood.
Chronic stress is the number one cause of sleep deprivation and is regarded a twenty-first century health epidemic. The high cortisol levels released during a prolonged stress state, exert negative effects on the circadian rhythm. Other melatonin blockers include blue light emitted from our mobile devices, environmental toxins and poor nutrition. All these modern-life melatonin disruptors work together to take us onto a new negative sleep-cycle journey.
Hormones are deeply interconnected with sleep, mood, and overall well-being and we can all strive to achieve optimal health and happiness.
Functional medicine understands that melatonin production also occurs within the gut cells. Gut absorption is crucial for providing the body with the essential vitamins and minerals involved in the complex reactions of melatonin synthesis. Stress pathways compete for and exhaust these essential nutrients. Therefore, optimising gut health and reducing stress is central to obtaining a good night’s sleep. Understanding this human pattern empowers us to make better lifestyle and nutritional choices to improve our mood and overall health and wellbeing.
Melatonin is in fact a super-hormone with multiple benefits outside of the sleep-cycle. There are numerous studies showing the importance of melatonin in anti-ageing, brain cell regeneration, boosting immunity, hormonal balance, optimising gut health, and improving resilience; all of which also affect our mood balance.
Tryptophan is an amino acid that helps produce melatonin.
B-vitamins facilitate the conversion of melatonin from serotonin.
Melatonin is also produced within the gut.
Blue light blocks melatonin production.
Warm baths and magnesium help relax the body and muscles.
Meditation reduces stress hormones, which can block the production of melatonin.
Acupressure stimulates the parasympathetic system triggering deep relaxation.
Melatonin synthesis peaks in the early hours and then begins to slowly decline.
Sunlight is required to produce serotonin which converts into melatonin.
More tips can be found on Instagram @functionaldoctoruk.
Dr Suman Gupta is a leading expert in the field of Functional Medicine with over 18 years’ experience as an NHS GP. She has helped thousands of people reverse chronic disease and reach their optimal health by getting to the root cause through ground-breaking comprehensive testing and formulating individualised treatment options.
She is the founder of the London Functional Doctor clinic www.functionaldoctor.co.uk; which provides lifestyle and nutritional treatment packages to optimise health and well-being. Regulated by the Care Quality Commission (CQC) for its management and governance, Functional Doctor is also in the process of launching nationwide online well-being packages as an introduction to Functional Medicine.
October
13/10/2025 - 17/10/2025 (All Day)(GMT+00:00)
The ground-breaking nationwide celebration of women in technology returns, featuring a week of dynamic online and
The ground-breaking nationwide celebration of women in technology returns, featuring a week of dynamic online and in-person events. Focused on career growth, networking, and innovation, this event continues to champion equality and empower women in the tech industry.
WeAreTechWomen is proud to present the second annual UK Women in Tech Week, taking place from October 13th to 17th, once again aligning with Ada Lovelace Day. This nationwide initiative brings together a vibrant line-up of virtual and in-person events celebrating the impact of women across the tech industry.
In partnership with leading organisations and Women in Tech networks, the week will offer inspiring panels, practical workshops, and meaningful networking opportunities. Through our website, attendees can easily book their spots for these events. Our master calendar for bookings will be released in the summer. Those who have registered their interest will receive priority booking.
Despite growing awareness, the sector still faces systemic challenges. Our upcoming Lovelace Report with Oliver Wyman has highlighted a number of issues around the broken systems that hinder the progression of women in the tech industry. Several reports over the past few years, including the Lovelace Report, cite that women are leaving the industry altogether. This talent drain is not only a loss of potential but is actively costing the UK economy billions of pounds each year.
With just 20% of the UK’s tech workforce made up of women—and with government commitments to scale the AI workforce—this is not the time to slow down. It’s time to step up.
For more information visit: women-in-tech-week.com
01nov09:0016:30KIN: Know. Inspire. Navigate | A Day for Women to Realign, Renew, and Rise
01/11/2025 09:00 - 16:30(GMT+00:00)
Henley Business School, Greenlands
Henley-on-Thames, RG9 3AU
Set on the tranquil banks of the River Thames, Henley’s historic Greenlands campus offers the perfect backdrop for a day of reflection, connection, and
Designed for early to mid-career women across industries who want practical tools they can use immediately, this one-day retreat follows the Kinspace KIN framework – Know, Inspire, Navigate – guiding you to:
This is not just a feel-good day. It’s sustainable learning – you will leave with your own action and implementation plan tailored to your life, so you can apply what you’ve learned immediately and keep building momentum long after the retreat.
In the afternoon, slow down and reconnect with your senses in a mindful pressed flower card crafting, writing to self and picture workshop. We’ll ask a few questions ahead of time so we can pair you by goals and stage, and tailor examples to your context. Then, step outdoors for a unique partner reflection in nature – partnering with both the landscape and each other to inspire deeper insight and grounded action.
To help you stay accountable and supported, you’ll have the option to join three monthly follow-up group sessions (at a separate price) designed to check in on your progress, troubleshoot challenges, and keep you moving towards your goals.
This is a confidential and supportive space with limited seats to ensure meaningful connection and participation.
Date: Saturday 1 November 2025
Time: 9:00 AM -4:30 PMT
Location: Henley Business School, Greenlands Henley-on-Thames
RG9 3AU
Price: £250 – Early Bird £200 until 10 September